Protective Vascular and Cardiac Effects of Inducible Nitric Oxide Synthase in Mice with Hyperhomocysteinemia

Diet-induced hyperhomocysteinemia produces endothelial and cardiac dysfunction and promotes thrombosis through a mechanism proposed to involve oxidative stress. Inducible nitric oxide synthase (iNOS) is upregulated in hyperhomocysteinemia and can generate superoxide. We therefore tested the hypothes...

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Detalhes bibliográficos
Main Authors: Dayal, Sanjana, Blokhin, Ilya O., Erger, Rochelle A., Jensen, Melissa, Arning, Erland, Stevens, Jeff W., Bottiglieri, Teodoro, Faraci, Frank M., Lentz, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167199/
https://ncbi.nlm.nih.gov/pubmed/25226386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107734
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