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GoIFISH: a system for the quantification of single cell heterogeneity from IFISH images

Molecular analysis has revealed extensive intra-tumor heterogeneity in human cancer samples, but cannot identify cell-to-cell variations within the tissue microenvironment. In contrast, in situ analysis can identify genetic aberrations in phenotypically defined cell subpopulations while preserving t...

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Bibliografske podrobnosti
Main Authors: Trinh, Anne, Rye, Inga H, Almendro, Vanessa, Helland, Åslaug, Russnes, Hege G, Markowetz, Florian
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167144/
https://ncbi.nlm.nih.gov/pubmed/25168174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0442-y
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