Silencing Bruton's tyrosine kinase in alveolar neutrophils protects mice from LPS/immune complex-induced acute lung injury

Previous observations made by our laboratory indicate that Bruton's tyrosine kinase (Btk) may play an important role in the pathophysiology of local inflammation in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). We have shown that there is cross talk between FcγRIIa and TLR...

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Auteurs principaux: Krupa, Agnieszka, Fol, Marek, Rahman, Moshiur, Stokes, Karen Y., Florence, Jon M., Leskov, Igor L., Khoretonenko, Mikhail V., Matthay, Michael A., Liu, Kathleen D., Calfee, Carolyn S., Tvinnereim, Amy, Rosenfield, Gabriel R., Kurdowska, Anna K.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166786/
https://ncbi.nlm.nih.gov/pubmed/25085625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00234.2013
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