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Interactive roles of CD73 and tissue nonspecific alkaline phosphatase in the renal vascular metabolism of 5′-AMP

CD73 metabolizes extracellular 5′-AMP to adenosine; yet recent experiments in brain tissue suggest that CD73 is not required for the metabolism of 5′-AMP to adenosine because of tissue nonspecific alkaline phosphatase (TNAP), which like CD73 is a GPI-anchored ecto-enyzme with 5′-nucleotidase activit...

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Bibliografiska uppgifter
Huvudupphovsmän: Jackson, Edwin K., Cheng, Dongmei, Verrier, Jonathan D., Janesko-Feldman, Keri, Kochanek, Patrick M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166734/
https://ncbi.nlm.nih.gov/pubmed/24990899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00312.2014
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