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Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases
TAL-effector nucleases (TALENs) are attractive tools for sequence-specific genome modifications, but their delivery still remains problematic. It is well known that the presence of multiple sequence repeats in TALEN genes hampers the use of lentiviral vectors. We report that lentiviral vectors readi...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4166709/ https://ncbi.nlm.nih.gov/pubmed/25230987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06409 |
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