Differential dopamine receptor subtype regulation of adenylyl cyclases in lipid rafts in human embryonic kidney and renal proximal tubule cells

Dopamine D(1)-like receptors (D(1)R and D(5)R) stimulate adenylyl cyclase (AC) activity, whereas the D(2)-like receptors (D(2), D(3) and D(4)) inhibit AC activity. D(1)R, but not the D(5)R, has been reported to regulate AC activity in lipid rafts (LRs). We tested the hypothesis that D(1)R and D(5)R...

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Main Authors: Yu, Peiying, Sun, Min, Villar, Van Anthony M., Zhang, Yanrong, Weinman, Edward J., Felder, Robin A., Jose, Pedro A.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166567/
https://ncbi.nlm.nih.gov/pubmed/25049074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.07.003
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