Differential dopamine receptor subtype regulation of adenylyl cyclases in lipid rafts in human embryonic kidney and renal proximal tubule cells

Dopamine D(1)-like receptors (D(1)R and D(5)R) stimulate adenylyl cyclase (AC) activity, whereas the D(2)-like receptors (D(2), D(3) and D(4)) inhibit AC activity. D(1)R, but not the D(5)R, has been reported to regulate AC activity in lipid rafts (LRs). We tested the hypothesis that D(1)R and D(5)R...

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Bibliografiske detaljer
Main Authors: Yu, Peiying, Sun, Min, Villar, Van Anthony M., Zhang, Yanrong, Weinman, Edward J., Felder, Robin A., Jose, Pedro A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166567/
https://ncbi.nlm.nih.gov/pubmed/25049074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.07.003
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