Differential dopamine receptor subtype regulation of adenylyl cyclases in lipid rafts in human embryonic kidney and renal proximal tubule cells

Dopamine D(1)-like receptors (D(1)R and D(5)R) stimulate adenylyl cyclase (AC) activity, whereas the D(2)-like receptors (D(2), D(3) and D(4)) inhibit AC activity. D(1)R, but not the D(5)R, has been reported to regulate AC activity in lipid rafts (LRs). We tested the hypothesis that D(1)R and D(5)R...

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Detalhes bibliográficos
Main Authors: Yu, Peiying, Sun, Min, Villar, Van Anthony M., Zhang, Yanrong, Weinman, Edward J., Felder, Robin A., Jose, Pedro A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166567/
https://ncbi.nlm.nih.gov/pubmed/25049074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.07.003
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