PLCB3 is a key modulator of IL-8 expression in cystic fibrosis bronchial epithelial cells

Respiratory insufficiency is the major cause of morbidity and mortality in patients affected by cystic fibrosis. An excessive neutrophilic inflammation, mainly orchestrated by the release of IL-8 from bronchial epithelial cells and amplified by chronic bacterial infection with Pseudomonas aeruginosa...

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Main Authors: Bezzerri, Valentino, d’Adamo, Pio, Rimessi, Alessandro, Lanzara, Carmen, Crovella, Sergio, Nicolis, Elena, Tamanini, Anna, Athanasakis, Emmanouil, Tebon, Maela, Bisoffi, Giulia, Drumm, Mitchell L., Knowles, Michael R., Pinton, Paolo, Gasparini, Paolo, Berton, Giorgio, Cabrini, Giulio
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166552/
https://ncbi.nlm.nih.gov/pubmed/21411730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003535
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