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Archaerhodopsin Variants with Enhanced Voltage Sensitive Fluorescence in Mammalian and Caenorhabditis elegans Neurons

Probing the neural circuit dynamics underlying behavior would benefit greatly from improved genetically encoded voltage indicators. The proton pump Archaerhodopsin-3 (Arch), an optogenetic tool commonly used for neuronal inhibition, has been shown to emit voltage sensitive fluorescence. Here we repo...

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Hlavní autoři: Flytzanis, Nicholas C., Bedbrook, Claire N., Chiu, Hui, Engqvist, Martin K. M., Xiao, Cheng, Chan, Ken Y., Sternberg, Paul W., Arnold, Frances H., Gradinaru, Viviana
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166526/
https://ncbi.nlm.nih.gov/pubmed/25222271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5894
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