Ubiquitylation of Autophagy Receptor Optineurin by HACE1 Activates Selective Autophagy for Tumor Suppression

In selective autophagy, receptors are central for cargo selection and delivery. However, it remains yet unclear whether and how multiple autophagy receptors might form complex and function concertedly to control autophagy. Optineurin (OPTN), implicated genetically in glaucoma and amyotrophic lateral...

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Autors principals: Liu, Zhengzhao, Chen, Peng, Gao, Hong, Gu, Yu, Yang, Jiao, Peng, Hong, Xu, Xingxing, Wang, Haifeng, Yang, Meiqiang, Liu, Xiaoying, Fan, Libin, Chen, Shiyao, Zhou, Jian, Sun, Yihong, Ruan, Kangchen, Cheng, Shuqun, Komatsu, Masaaki, White, Eileen, Li, Lin, Ji, Hongbin, Finley, Daniel, Hu, Ronggui
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166492/
https://ncbi.nlm.nih.gov/pubmed/25026213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.05.015
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