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Rapid establishment of a HEK 293 cell line expressing FVIII-BDD using AAV site-specific integration plasmids
BACKGROUND: Stable human cell lines have gradually become the preferred system for large scale production of recombinant proteins for clinical applications because of their capacity of proper protein post-translational modification and low immunogenicity. However, human cell line development technol...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4166473/ https://ncbi.nlm.nih.gov/pubmed/25204455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-626 |
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