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Oxygen differentially affects the hox proteins Hoxb5 and Hoxa5 altering airway branching and lung vascular formation

Hoxb5 and Hoxa5 transcription factor proteins uniquely impact lung morphogenesis at the developmental time point when extremely preterm infants are born. The effect of O(2) exposure (0.4 FiO(2)) used in preterm infant care on these Hox proteins is unknown. We used ex vivo fetal mouse lung organ cult...

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Bibliografske podrobnosti
Main Authors: Silfa-Mazara, Francheyska, Mujahid, Sana, Thomas, Courtney, Vong, Thxuan, Larsson, Ingrid, Nielsen, Heber C., Volpe, MaryAnn V.
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165823/
https://ncbi.nlm.nih.gov/pubmed/25073509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-014-0237-7
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