Establishment of a novel CCR5 and CXCR4 expressing CD4(+ )cell line which is highly sensitive to HIV and suitable for high-throughput evaluation of CCR5 and CXCR4 antagonists
BACKGROUND: CCR5 and CXCR4 are the two main coreceptors essential for HIV entry. Therefore, these chemokine receptors have become important targets in the search for anti-HIV agents. Here, we describe the establishment of a novel CD4(+ )cell line, U87.CD4.CCR5.CXCR4, stably expressing both CCR5 and...
Uloženo v:
| Vydáno v: | Retrovirology |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BMC
2004
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC416571/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15169555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1742-4690-1-2 |
| Tagy: |
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|