The protein phosphatase 2A regulatory subunit B55α is a modulator of signaling and microRNA expression in acute myeloid leukemia cells

We recently discovered that the protein phosphatase 2A (PP2A) B55α subunit (PPP2R2A) is under-expressed in primary blast cells and is unfavorable for remission duration in AML patients. In this study, reverse phase protein analysis (RPPA) of 230 proteins in 511 AML patient samples revealed a strong...

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Main Authors: Ruvolo, Peter P., Ruvolo, Vivian R., Jacamo, Rodrigo, Burks, Jared K., Zeng, Zhihong, Duvvuri, Seshagiri R., Zhou, Liran, Qiu, Yihua, Coombes, Kevin R., Zhang, Nianxiang, Yoo, Suk Y., Pan, Rongqing, Hail, Numsen, Konopleva, Marina, Calin, George, Kornblau, Steven M., Andreeff, Michael
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165504/
https://ncbi.nlm.nih.gov/pubmed/24858343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.05.006
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