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Kaposi's Sarcoma-Associated Herpesvirus-Encoded Latency-Associated Nuclear Antigen Inhibits Lytic Replication by Targeting Rta: a Potential Mechanism for Virus-Mediated Control of Latency

Like other herpesviruses, Kaposi's sarcoma-associated herpesvirus (KSHV, also designated human herpesvirus 8) can establish a latent infection in the infected host. During latency a small number of genes are expressed. One of those genes encodes latency-associated nuclear antigen (LANA), which...

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Autori principali: Lan, Ke, Kuppers, Daniel A., Verma, Subhash C., Robertson, Erle S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC416549/
https://ncbi.nlm.nih.gov/pubmed/15163750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.12.6585-6594.2004
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