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Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and the risk of primary Hepatocellular Carcinoma (HCC) in a Chinese population

OBJECTIVES: Methylenetetrahydrofolate reductase (MTHFR), which is expressed in the liver, may be involved in both DNA methylation and DNA synthesis. It is also indicated as a potential risk factor of liver cancer in patients with chronic liver disease. To date, no study has been conducted on MTHFR a...

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Detalhes bibliográficos
Main Authors: Mu, Li-Na, Cao, Wei, Zhang, Zuo-Feng, Cai, Lin, Jiang, Qing-Wu, You, Nai-Chieh, Goldstein, Binh Yang, Wei, Guo-Rong, Chen, Chuan-Wei, Lu, Qing-Yi, Zhou, Xue-Fu, Ding, Bao-Guo, Chang, Jun, Yu, Shun-Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165489/
https://ncbi.nlm.nih.gov/pubmed/17503006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-007-9012-x
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