5,10-Methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms in patients with nonsyndromic cleft lip and palate

Cleft lip with or without cleft palate (CL/P) is considered a multifactorial genetic disorder. Folic acid metabolism has been suggested to underlie the development of CL/P. The gene for the enzyme 5,10-methylentetrahydrofolate reductase (MTHFR) contributes to folic acid metabolism, and polymorphisms...

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Vydáno v:Biomed Rep
Hlavní autoři: Komiyama, Yuske, Koshiji, Chikako, Yoshida, Waka, Natsume, Nagato, Kawamata, Hitoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583695/
https://ncbi.nlm.nih.gov/pubmed/33123371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2020.1364
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