A Chimeric Porcine Circovirus (PCV) with the Immunogenic Capsid Gene of the Pathogenic PCV Type 2 (PCV2) Cloned into the Genomic Backbone of the Nonpathogenic PCV1 Induces Protective Immunity against PCV2 Infection in Pigs

Porcine circovirus type 2 (PCV2) is associated with postweaning multisystemic wasting syndrome in pigs, whereas PCV1 is nonpathogenic. We previously demonstrated that a chimeric PCV1-2 virus (with the immunogenic capsid gene of PCV2 cloned into the backbone of PCV1) induces an antibody response to t...

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Detalhes bibliográficos
Main Authors: Fenaux, M., Opriessnig, T., Halbur, P. G., Elvinger, F., Meng, X. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC416547/
https://ncbi.nlm.nih.gov/pubmed/15163723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.12.6297-6303.2004
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