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Is DHT Production by 5α-Reductase Friend or Foe in Prostate Cancer?

The first advance in the history of studies on prostate cancer (PCa) and androgens was the development of treatment with castration and administration of estrogen by Charles B. Huggins, who won the Nobel Prize in Physiology and Medicine. Since then, and for 70 years, androgen deprivation therapy has...

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Autores principales: Kosaka, Takeo, Miyajima, Akira, Oya, Mototsugu
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165281/
https://ncbi.nlm.nih.gov/pubmed/25279351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00247
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