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Amplification of Tau Fibrils from Minute Quantities of Seeds

[Image: see text] The propagation of Tau pathology in Alzheimer’s disease (AD) is thought to proceed through templated conversion of Tau protein into fibrils and cell-to-cell transfer of elongation-competent seeds. To investigate the efficiency of Tau conversion, we adapted the protein misfolding cy...

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Bibliografiske detaljer
Main Authors: Meyer, Virginia, Dinkel, Paul D., Rickman Hager, Emily, Margittai, Martin
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165214/
https://ncbi.nlm.nih.gov/pubmed/25153692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501050g
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