Interleukin-13 Overexpression by Tax Transactivation: a Potential Autocrine Stimulus in Human T-Cell Leukemia Virus-Infected Lymphocytes

The human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein induces growth transformation and is critical for the pathogenesis of the HTLV-1-induced adult T-cell leukemia (ATL). It stimulates the cell cycle and transactivates cellular genes. Here we show that the expression of interleukin-13 (IL...

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Bibliographische Detailangaben
Hauptverfasser: Wäldele, Katja, Schneider, Grit, Ruckes, Tobias, Grassmann, Ralph
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Transformation and Oncogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC416520/
https://ncbi.nlm.nih.gov/pubmed/15163701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.12.6081-6090.2004
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