Proteolytic Cleavage of the Catalytic Subunit of DNA-Dependent Protein Kinase during Poliovirus Infection

DNA-dependent protein kinase (DNA-PK) is a serine/threonine kinase that has critical roles in DNA double-strand break repair, as well as B- and T-cell antigen receptor rearrangement. The DNA-PK enzyme consists of the Ku regulatory subunit and a 450-kDa catalytic subunit termed DNA-PK(CS). Both of th...

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Detalhes bibliográficos
Main Authors: Graham, Kareem L., Gustin, Kurt E., Rivera, Carlos, Kuyumcu-Martinez, N. Muge, Choe, Sunny S., Lloyd, Richard E., Sarnow, Peter, Utz, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC416498/
https://ncbi.nlm.nih.gov/pubmed/15163725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.12.6313-6321.2004
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