Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival

Unless mitigated, external and physiological stresses are detrimental for cells, especially in mitosis, resulting in chromosomal missegregation, aneuploidy, or apoptosis. Heat shock proteins (Hsps) maintain protein homeostasis and promote cell survival. Hsps are transcriptionally regulated by heat s...

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Main Authors: Elsing, Alexandra N., Aspelin, Camilla, Björk, Johanna K., Bergman, Heidi A., Himanen, Samu V., Kallio, Marko J., Roos-Mattjus, Pia, Sistonen, Lea
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2014
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164949/
https://ncbi.nlm.nih.gov/pubmed/25202032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201402002
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