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Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival

Unless mitigated, external and physiological stresses are detrimental for cells, especially in mitosis, resulting in chromosomal missegregation, aneuploidy, or apoptosis. Heat shock proteins (Hsps) maintain protein homeostasis and promote cell survival. Hsps are transcriptionally regulated by heat s...

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Detalhes bibliográficos
Main Authors: Elsing, Alexandra N., Aspelin, Camilla, Björk, Johanna K., Bergman, Heidi A., Himanen, Samu V., Kallio, Marko J., Roos-Mattjus, Pia, Sistonen, Lea
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164949/
https://ncbi.nlm.nih.gov/pubmed/25202032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201402002
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