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Heterozygous Deletion of Ventral Anterior Homeobox (Vax1) Causes Subfertility in Mice

The known genetic causes of idiopathic hypogonadotropic hypogonadism (IHH) are often associated with the loss of GnRH neurons, leading to the disruption of the hypothalamic pituitary gonadal axis and subfertility. The majority of IHH cases have unknown origins and likely arise from compound mutation...

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Detalhes bibliográficos
Main Authors: Hoffmann, Hanne M., Tamrazian, Anika, Xie, Huimin, Pérez-Millán, María Inés, Kauffman, Alexander S., Mellon, Pamela L.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164932/
https://ncbi.nlm.nih.gov/pubmed/25060364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1277
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