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The genetic basis of obesity-associated type 2 diabetes (diabesity) in polygenic mouse models

Obesity-associated diabetes (“diabesity”) in mouse strains is characterized by severe insulin resistance, hyperglycaemia and progressive failure, and loss of beta cells. This condition is observed in inbred obese mouse strains such as the New Zealand Obese (NZO/HlLt and NZO/HlBomDife) or the TALLYHO...

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Detalhes bibliográficos
Main Authors: Joost, Hans-Georg, Schürmann, Annette
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164836/
https://ncbi.nlm.nih.gov/pubmed/24752583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-014-9514-2
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