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The genetic basis of obesity-associated type 2 diabetes (diabesity) in polygenic mouse models

Obesity-associated diabetes (“diabesity”) in mouse strains is characterized by severe insulin resistance, hyperglycaemia and progressive failure, and loss of beta cells. This condition is observed in inbred obese mouse strains such as the New Zealand Obese (NZO/HlLt and NZO/HlBomDife) or the TALLYHO...

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Bibliografische gegevens
Hoofdauteurs: Joost, Hans-Georg, Schürmann, Annette
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164836/
https://ncbi.nlm.nih.gov/pubmed/24752583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-014-9514-2
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