Resistance to Noise-Induced Hearing Loss in 129S6 and MOLF Mice: Identification of Independent, Overlapping, and Interacting Chromosomal Regions

Noise-induced hearing loss (NIHL) is a prevalent health risk. Inbred mouse strains 129S6/SvEvTac (129S6) and MOLF/EiJ (MOLF) show strong NIHL resistance (NR) relative to CBA/CaJ (CBACa). In this study, we developed quantitative trait locus (QTL) maps for NR. We generated F1 animals by intercrossing...

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Autori principali: Street, Valerie A., Kujawa, Sharon G., Manichaikul, Ani, Broman, Karl W., Kallman, Jeremy C., Shilling, Dustin J., Iwata, Ayaka J., Robinson, Linda C., Robbins, Carol A., Li, Jin, Liberman, M. Charles, Tempel, Bruce L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164691/
https://ncbi.nlm.nih.gov/pubmed/24952082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-014-0472-x
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