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Synaptopathy in the noise-exposed and aging cochlea: primary neural degeneration in acquired sensorineural hearing loss

The classic view of sensorineural hearing loss (SNHL) is that the “primary” targets are hair cells, and that cochlear-nerve loss is “secondary” to hair cell degeneration. Our recent work in mouse and guinea pig has challenged that view. In noise-induced hearing loss, exposures causing only reversibl...

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Detalhes bibliográficos
Publicado no:Hear Res
Main Authors: Kujawa, Sharon G., Liberman, M. Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567542/
https://ncbi.nlm.nih.gov/pubmed/25769437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2015.02.009
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