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Resistance to Noise-Induced Hearing Loss in 129S6 and MOLF Mice: Identification of Independent, Overlapping, and Interacting Chromosomal Regions

Noise-induced hearing loss (NIHL) is a prevalent health risk. Inbred mouse strains 129S6/SvEvTac (129S6) and MOLF/EiJ (MOLF) show strong NIHL resistance (NR) relative to CBA/CaJ (CBACa). In this study, we developed quantitative trait locus (QTL) maps for NR. We generated F1 animals by intercrossing...

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Detalhes bibliográficos
Main Authors: Street, Valerie A., Kujawa, Sharon G., Manichaikul, Ani, Broman, Karl W., Kallman, Jeremy C., Shilling, Dustin J., Iwata, Ayaka J., Robinson, Linda C., Robbins, Carol A., Li, Jin, Liberman, M. Charles, Tempel, Bruce L
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164691/
https://ncbi.nlm.nih.gov/pubmed/24952082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-014-0472-x
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