Resistance to Noise-Induced Hearing Loss in 129S6 and MOLF Mice: Identification of Independent, Overlapping, and Interacting Chromosomal Regions

Noise-induced hearing loss (NIHL) is a prevalent health risk. Inbred mouse strains 129S6/SvEvTac (129S6) and MOLF/EiJ (MOLF) show strong NIHL resistance (NR) relative to CBA/CaJ (CBACa). In this study, we developed quantitative trait locus (QTL) maps for NR. We generated F1 animals by intercrossing...

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Hauptverfasser: Street, Valerie A., Kujawa, Sharon G., Manichaikul, Ani, Broman, Karl W., Kallman, Jeremy C., Shilling, Dustin J., Iwata, Ayaka J., Robinson, Linda C., Robbins, Carol A., Li, Jin, Liberman, M. Charles, Tempel, Bruce L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164691/
https://ncbi.nlm.nih.gov/pubmed/24952082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-014-0472-x
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