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Detection of evolutionarily stable fragments of cellular pathways by hierarchical clustering of phyletic patterns

BACKGROUND: Phyletic patterns denote the presence and absence of orthologous genes in completely sequenced genomes and are used to infer functional links between genes, on the assumption that genes involved in the same pathway or functional system are co-inherited by the same set of genomes. However...

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Hlavní autoři: Glazko, Galina V, Mushegian, Arcady R
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC416468/
https://ncbi.nlm.nih.gov/pubmed/15128446
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