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Detection of evolutionarily stable fragments of cellular pathways by hierarchical clustering of phyletic patterns

BACKGROUND: Phyletic patterns denote the presence and absence of orthologous genes in completely sequenced genomes and are used to infer functional links between genes, on the assumption that genes involved in the same pathway or functional system are co-inherited by the same set of genomes. However...

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Bibliographic Details
Main Authors: Glazko, Galina V, Mushegian, Arcady R
Format: Artigo
Language:Inglês
Published: BioMed Central 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC416468/
https://ncbi.nlm.nih.gov/pubmed/15128446
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