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Effects of traumatic brain injury on reactive astrogliosis and seizures in mouse models of Alexander disease

Alexander disease (AxD) is the only known human pathology caused by mutations in an astrocyte-specific gene, glial fibrillary acidic protein (GFAP). These mutations result in abnormal GFAP accumulations that promote seizures, motor delays and, ultimately, death. The exact contribution of increased,...

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Detalhes bibliográficos
Main Authors: Cotrina, Maria Luisa, Chen, Michael, Han, Xiaoning, Iliff, Jeffrey, Ren, Zeguang, Sun, Wei, Hagemann, Tracy, Goldman, James, Messing, Albee, Nedergaard, Maiken
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164594/
https://ncbi.nlm.nih.gov/pubmed/25069089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2014.07.029
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