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Ca(2+)/Calcineurin-Dependent Inactivation of Neuronal L-type Ca(2+) Channels Requires Priming by AKAP-Anchored Protein Kinase A
Within neurons, Ca(2+)-dependent inactivation (CDI) of voltage-gated L-type Ca(2+) channels shapes cytoplasmic Ca(2+) signals. CDI is initiated by Ca(2+) binding to channel-associated calmodulin and subsequent Ca(2+)/calmodulin activation of the Ca(2+)-dependent phosphatase, calcineurin (CaN), which...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4164350/ https://ncbi.nlm.nih.gov/pubmed/24835998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.04.039 |
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