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Evidence for distinct mechanisms of uptake and antitumor activity of secretory phospholipase A(2) responsive liposome in prostate cancer

Secretory phospholipase A(2) (sPLA(2)) cleave phospholipids at sn-2 ester bonds, releasing lysophospholipids and fatty acids, and are over expressed in several pathologies, including inflammation, arthritis, sepsis and breast and prostate cancers. Herein we evaluated the therapeutic activity of lipo...

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Detalhes bibliográficos
Main Authors: Mock, JN, Costyn, LJ, Wilding, SL, Arnold, RD, Cummings, BS
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164335/
https://ncbi.nlm.nih.gov/pubmed/22890797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ib20108a
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