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Enhanced antitumor activity of low-dose continuous administration schedules of topotecan in prostate cancer

PURPOSE: The objective of this study was to determine the antitumor effects of alternate dosing schedules of topotecan in prostate cancer. RESULTS: A concentration-dependent increase in cytotoxicity was observed in PC-3 and LNCaP cells after topotecan treatment using conventional and metronomic prot...

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Detalhes bibliográficos
Main Authors: Aljuffali, Ibrahim A, Mock, Jason N, Costyn, Leah J, Nguyen, Ha, Nagy, Tamas, Cummings, Brian S, Arnold, Robert D
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230472/
https://ncbi.nlm.nih.gov/pubmed/21709443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.12.5.15950
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