Role of CTCF Binding Sites in the Igf2/H19 Imprinting Control Region

A ∼2.4-kb imprinting control region (ICR) regulates somatic monoallelic expression of the Igf2 and H19 genes. This is achieved through DNA methylation-dependent chromatin insulator and promoter silencing activities on the maternal and paternal chromosomes, respectively. In somatic cells, the hypomet...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Szabó, Piroska E., Tang, Shih-Huey E., Silva, Francisco J., Tsark, Walter M. K., Mann, Jeffrey R.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2004
Fag:	Transcriptional Regulation
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC416431/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15143173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.11.4791-4800.2004
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!