Insulin transcriptionally regulates argininosuccinate synthase to maintain vascular endothelial function

Diminished vascular endothelial cell nitric oxide (NO) production is a major factor in the complex pathogenesis of diabetes mellitus. In this report, we demonstrate that insulin not only maintains endothelial NO production through regulation of endothelial nitric oxide synthase (eNOS), but also via...

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Bibliographic Details
Main Authors: Haines, Ricci J, Corbin, Karen D, Pendleton, Laura C, Meininger, Cynthia J, Eichler, Duane C
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164166/
https://ncbi.nlm.nih.gov/pubmed/22452988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.03.074
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