Glucocorticoids and Tumor Necrosis Factor Alpha Cooperatively Regulate Toll-Like Receptor 2 Gene Expression

Tumor necrosis factor alpha (TNF-α) and glucocorticoids are widely recognized as mutually antagonistic regulators of adaptive immunity and inflammation. Surprisingly, we show here that they cooperatively regulate components of innate immunity. The Toll-like receptor 2 (TLR2) gene encodes a transmemb...

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Bibliographic Details
Main Authors: Hermoso, Marcela A., Matsuguchi, Tetsuya, Smoak, Kathleen, Cidlowski, John A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC416411/
https://ncbi.nlm.nih.gov/pubmed/15143169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.11.4743-4756.2004
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