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Stimulus-Specific Assembly of Enhancer Complexes on the Tumor Necrosis Factor Alpha Gene Promoter

The human tumor necrosis factor alpha (TNF-α) gene is rapidly activated in response to multiple signals of stress and inflammation. We have identified transcription factors present in the TNF-α enhancer complex in vivo following ionophore stimulation (ATF-2/Jun and NFAT) and virus infection (ATF-2/J...

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Detalhes bibliográficos
Main Authors: Falvo, James V., Uglialoro, Adele M., Brinkman, Brigitta M. N., Merika, Menie, Parekh, Bhavin S., Tsai, Eunice Y., King, Hadley C., Morielli, Anthony D., Peralta, Ernest G., Maniatis, Tom, Thanos, Dimitris, Goldfeld, Anne E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110840/
https://ncbi.nlm.nih.gov/pubmed/10688670
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