Stimulus-Specific Assembly of Enhancer Complexes on the Tumor Necrosis Factor Alpha Gene Promoter

The human tumor necrosis factor alpha (TNF-α) gene is rapidly activated in response to multiple signals of stress and inflammation. We have identified transcription factors present in the TNF-α enhancer complex in vivo following ionophore stimulation (ATF-2/Jun and NFAT) and virus infection (ATF-2/J...

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Autori principali: Falvo, James V., Uglialoro, Adele M., Brinkman, Brigitta M. N., Merika, Menie, Parekh, Bhavin S., Tsai, Eunice Y., King, Hadley C., Morielli, Anthony D., Peralta, Ernest G., Maniatis, Tom, Thanos, Dimitris, Goldfeld, Anne E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
Soggetti:
Transcriptional Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC110840/
https://ncbi.nlm.nih.gov/pubmed/10688670
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