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Structural insights into the transcription-independent apoptotic pathway of p53

Reactivating the p53 pathway in tumors is an important strategy for anticancer therapy. In response to diverse cellular stresses, the tumor suppressor p53 mediates apoptosis in a transcriptionindependent and transcription-dependent manner. Although extensive studies have focused on the transcription...

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Autor principal: Chi, Seung-Wook
Format: Artigo
Idioma:Inglês
Publicat: Korean Society for Biochemistry and Molecular Biology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163879/
https://ncbi.nlm.nih.gov/pubmed/24499665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2014.47.3.261
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