CBX7 gene expression plays a negative role in adipocyte cell growth and differentiation

We have recently generated knockout mice for the Cbx7 gene, coding for a polycomb group protein that is downregulated in human malignant neoplasias. These mice develop liver and lung adenomas and carcinomas, which confirms a tumour suppressor role for CBX7. The CBX7 ability to downregulate CCNE1 exp...

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Bibliografiske detaljer
Main Authors: Forzati, Floriana, Federico, Antonella, Pallante, Pierlorenzo, Colamaio, Marianna, Esposito, Francesco, Sepe, Romina, Gargiulo, Sara, Luciano, Antonio, Arra, Claudio, Palma, Giuseppe, Bon, Giulia, Bucher, Stefania, Falcioni, Rita, Brunetti, Arturo, Battista, Sabrina, Fedele, Monica, Fusco, Alfredo
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163664/
https://ncbi.nlm.nih.gov/pubmed/25190058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20147872
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