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CBX7 gene expression plays a negative role in adipocyte cell growth and differentiation
We have recently generated knockout mice for the Cbx7 gene, coding for a polycomb group protein that is downregulated in human malignant neoplasias. These mice develop liver and lung adenomas and carcinomas, which confirms a tumour suppressor role for CBX7. The CBX7 ability to downregulate CCNE1 exp...
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Main Authors: | , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Company of Biologists
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4163664/ https://ncbi.nlm.nih.gov/pubmed/25190058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20147872 |
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