In vivo characterization of the role of tissue‐specific translation elongation factor 1A2 in protein synthesis reveals insights into muscle atrophy

Translation elongation factor 1A2 (eEF1A2), uniquely among translation factors, is expressed specifically in neurons and muscle. eEF1A2‐null mutant wasted mice develop an aggressive, early‐onset form of neurodegeneration, but it is unknown whether the wasting results from denervation of the muscles,...

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Detalhes bibliográficos
Main Authors: Doig, Jennifer, Griffiths, Lowri A., Peberdy, David, Dharmasaroja, Permphan, Vera, Maria, Davies, Faith J. C., Newbery, Helen J., Brownstein, David, Abbott, Catherine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies 2013
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163635/
https://ncbi.nlm.nih.gov/pubmed/24460877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12554
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