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EGFR-TKI resistance in NSCLC patients: mechanisms and strategies
The epidermal growth factor receptor (EGFR) is a kind of receptor tyrosine kinase (RTK) that plays a critical role in the initiation and development of malignant tumors via modulating downstream signaling pathways. In non-small cell lung cancer (NSCLC), the activating mutations located in the tyrosi...
Tallennettuna:
Päätekijät: | , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
e-Century Publishing Corporation
2014
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4163608/ https://ncbi.nlm.nih.gov/pubmed/25232485 |
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