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EGFR-TKI resistance in NSCLC patients: mechanisms and strategies

The epidermal growth factor receptor (EGFR) is a kind of receptor tyrosine kinase (RTK) that plays a critical role in the initiation and development of malignant tumors via modulating downstream signaling pathways. In non-small cell lung cancer (NSCLC), the activating mutations located in the tyrosi...

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Bibliografische gegevens
Hoofdauteurs: Lin, Yuxin, Wang, Xian, Jin, Hongchuan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163608/
https://ncbi.nlm.nih.gov/pubmed/25232485
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