EMT-Mediated Acquired EGFR-TKI Resistance in NSCLC: Mechanisms and Strategies

Acquired resistance inevitably limits the curative effects of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), which represent the classical paradigm of molecular-targeted therapies in non-small-cell lung cancer (NSCLC). How to break such a bottleneck becomes a pressing probl...

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Bibliografiske detaljer
Udgivet i:Front Oncol
Main Authors: Zhu, Xuan, Chen, Lijie, Liu, Ling, Niu, Xing
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798878/
https://ncbi.nlm.nih.gov/pubmed/31681582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01044
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