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EMT-Mediated Acquired EGFR-TKI Resistance in NSCLC: Mechanisms and Strategies
Acquired resistance inevitably limits the curative effects of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), which represent the classical paradigm of molecular-targeted therapies in non-small-cell lung cancer (NSCLC). How to break such a bottleneck becomes a pressing probl...
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| Publicado no: | Front Oncol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6798878/ https://ncbi.nlm.nih.gov/pubmed/31681582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01044 |
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