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The inositol 1,4,5-trisphosphate receptor is essential for T-cell receptor signaling.

Antigen-specific activation of T lymphocytes, via stimulation of the T-cell antigen receptor (TCR) complex, is marked by a rapid and sustained increase in the concentration of cytoplasmic free Ca2+ ([Ca2+]i). It has been suggested that the second messenger inositol 1,4,5-trisphosphate (IP3) produced...

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Bibliografski detalji
Glavni autori: Jayaraman, T, Ondriasová, E, Ondrias, K, Harnick, D J, Marks, A R
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC41631/
https://ncbi.nlm.nih.gov/pubmed/7597070
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