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Describing the genetic architecture of epilepsy through heritability analysis

Epilepsy is a disease with substantial missing heritability; despite its high genetic component, genetic association studies have had limited success detecting common variants which influence susceptibility. In this paper, we reassess the role of common variants on epilepsy using extensions of herit...

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Detalhes bibliográficos
Main Authors: Speed, Doug, O’Brien, Terence J., Palotie, Aarno, Shkura, Kirill, Marson, Anthony G., Balding, David J., Johnson, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163034/
https://ncbi.nlm.nih.gov/pubmed/25063994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu206
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